Wine consumption and intestinal redox homeostasis

Wine consumption and intestinal redox homeostasis

Regular consumption of moderate doses of wine is an integral part of the Mediterranean diet, which has long been considered to provide remarkable health benefits. Wine's beneficial effect has been attributed principally to its non-alcoholic portion, which has antioxidant properties, and contains a wide variety of phenolics, generally called polyphenols. Wine phenolics may prevent or delay the p...

Wine Consumption and Heart Disease

Redox regulated peroxisome homeostasis

Peroxisomes are ubiquitous organelles present in nearly all eukaryotic cells. Conserved functions of peroxisomes encompass beta-oxidation of fatty acids and scavenging of reactive oxygen species generated from diverse peroxisomal metabolic pathways. Peroxisome content, number, and size can change quickly in response to environmental and/or developmental cues. To achieve efficient peroxisome hom...

Diglycosyl diselenides alter redox homeostasis and glucose consumption of infective African trypanosomes

With the aim to develop compounds able to target multiple metabolic pathways and, thus, to lower the chances of drug resistance, we investigated the anti-trypanosomal activity and selectivity of a series of symmetric diglycosyl diselenides and disulfides. Of 18 compounds tested the fully acetylated forms of di-β-D-glucopyranosyl and di-β-D-galactopyranosyl diselenides (13 and 15, respectively) ...

Wine consumption and epithelial ovarian cancer.

We examined the relationship between consumption of specific alcoholic beverages, including wine, beer, and liquor, and risk of epithelial ovarian cancer using data from the Swedish Mammography Cohort, a population-based prospective study of 61,084 women ages 38 to 76 years at enrollment in 1987 to 1990. Information on consumption of alcoholic beverages was obtained through a mailed food freque...